Idiopathic pulmonary fibrosis (IPF) is a form of chronic progressive fibrotic lung disease with loss of normal lung tissue, restricted ventilation, impaired gas exchange, leading to respiratory symptoms, poor quality of life, considerable morbidity and mortality.
Rodent IPF model replicates key pathological features of human IPF, including the development of fibrotic lesions and impaired lung function, which makes it great for a new drug candidate efficacy testing.