Liver Fibrosis

Liver fibrosis represents a classical outcome of many chronic liver diseases irrespectively of the etiology of injury. It results from successive rounds or chronic activation of the physiological wound-healing response that sustains persistent fibrogenesis and leads to progressive fibrosis of the organ through inflammation or reactive oxygen species mechanism.

Study models:

CCI-4-induced liver fibrosis

HFHF-induced liver fibrosis

MCDD-induced liver fibrosis